This is the home-page of the Molecular Biotechnology Group of the Institute of Physics of São Carlos of the University of São Paulo. Our group is concerned with the study at a fundamental level of the structure and function of biomolecules and the use of this knowledge for the development of technical innovation.
Our research is based on molecular biology, chemical and computational techniques which form an interdisciplinary framework for tackling the molecular basis of biophysical phenomena and subsequent development of novel technologies. The laboratories are equipped with state-of-the-art equipments for protein expression, purification, crystallization and structure refinement, for the chemical analysis of biopolymer degradation and, finally, for the simulation and modeling of protein structures and substrates for a finer comprehension of the relationships between structure and function.
The principal research line being currently developed in our laboratories concern the study and optimization of enzymes for the degradation of biomass aiming the sustainable development of second generation biofuels, specially derived from sugar-cane.
Our group is also interested in the study of structure and function in Nuclear Hormone Receptors, crystallization and structure-refinement methods, and general computational methods in chemistry and biochemistry.